Apply for Research Funding

At the Lily Foundation, we are committed to finding a cure for Mitochondrial Disease through funding high quality medical research. It is vital that funds raised through the generosity of our donors are directed towards research which will give us the best chance of achieving this goal. 

The Lily Foundation is an NIHR non-commercial partner, which means eligible funding streams are automatically eligible for NIHR Clinical Research Network (CRN) support and therefore entitled to access NHS support via the NIHR Clinical Research Network.

Call For Applications - Precision Diagnostics for Mitochondrial Diseases

The Lily Foundation is seeking to fund translational research in diagnostics that could realistically be translated into clinical practice in the near future. The successful project(s) will demonstrate a highly collaborative approach, building on the existing NHS infrastructure and guaranteeing equity of access to undiagnosed patients likely to have mitochondrial disease. Applications should include emerging technologies not yet available through routine NHS diagnostic avenues, but which have promising data for improving diagnostics in the research setting. This call will build on the highly successful ‘Lily Exome’ initiative that delivered improved diagnostic rates at a time when exome sequencing was inaccessible in the public sector.

Call: Diagnosing Mitochondrial Disease 22/23

Status: OPEN

Opening Date: Monday 2nd May 2022 - 9am

Closing Date: Friday 3rd June 2022 - 5pm

Who can apply?

Any UK academic institution, ideally collaborating within an NHS diagnostic service. Principal investigators should have a permanent, open-ended or long-term rolling contract, salaried by a UK-based academic/research organisation.

Only one application per PI will be considered per funding round. Multisite applications are encouraged.

Grant Overview

We will fund a 24-48 month research project(s), up to a value of £150,000 per year. We are particularly interested in highly translational projects which create an infrastructure that seamlessly link with NHS diagnostic services.

Projects should include salary costs and consumables but no large items of equipment (£10,000 max).

How to apply?

Lily grant applicants should prepare a submission covering 5 key areas:

  • abstract on the potential treatment being investigated written in layman’s terms (max 100 words);
  • objectives, methodology and plan of investigation with clear timeline, including preliminary results from previous relevant studies (max 3 pages of A4);
  • summary of benefit to patients with mitochondrial disease (max 500 words);
  • full project budget (including funding detail from all other sources). Separate budget requested from Lily Foundation if not for the full project (max 1 page of A4);
  • research environment & supervisory team (max 500 words); please attach CVs of all key applicants (max 2 pages to include details of current research funding and 1 page of up to 10 recent and relevant publications.);
  • confirmation of whether you would be willing for your application to be shared confidentially with Lily research funding partners.

All submissions should be submitted as a single high quality pdf document incorporating all of the above.

Please note that applications which do not follow the prescribed format, will not be accepted for review.

Application Review

Applications will be evaluated by our international expert peer review panel, based on the following criteria: 

  • highly translational project likely to improve diagnostics in the medium term with strong equity of access for patients regardless of location, age, and family structure available for testing
  • scientific merit/ innovation, soundness of methodology & feasibility of achieving outcomes
  • budget details (reasonable, justified and potential value of investment to The Lily Foundation)
  • track record of investigator(s) & quality of research environment to perform work efficiently/accurately

Queries or completed applications should be emailed to [email protected]

Decisions will be announced by September 2022.

Call For Applications - Treatments for Mitochondrial Disease

Lily research grants will be offered to UK academic researchers and UK institutions that can demonstrate they are committed to discovering innovative treatments for Mitochondrial Disease. Clinical and preclinical treatment studies will be considered, provided they could realistically be expected to translate to clinical practice. Treatments are defined as reducing symptoms of Mitochondrial Disease, improving quality of life or lengthening lifespan of patients.

We are committed to investing a minimum of £200,000/year, towards research to develop new treatments for Mitochondrial Disease. 

Call: Treatments for Mitochondrial Disease 22/23

Status: PENDING

Opening Date: Monday 19th September 2022 - 9am

Closing Date:  Friday 18th November 2022 - 5pm

Who can apply?

Any UK academic institution. Principal investigators should have a permanent, open-ended or long-term rolling contract, salaried by a UK-based academic/research organisation.

Only one application per PI will be considered per funding round.

Grant Overview

We will fund 12-24 month research projects, up to a value of £100,000. We will consider funding projects outside this time frame and over £100,000 only if they could clearly lead to significant/direct patient benefit. We are particularly interested in encouraging applicants to apply for pilot funding or efficacy studies, to develop innovative concepts, with budgets of approximate £50-75,000.  

Projects should include salary costs and consumables but no large items of equipment (£10,000 max).

How to apply?

Lily grant applicants should prepare a submission covering 5 key areas:

  • abstract on the potential treatment being investigated written in layman’s terms (max 100 words);
  • objectives, methodology and plan of investigation with clear timeline, including preliminary results from previous relevant studies (max 3 pages of A4);
  • summary of benefit to patients with mitochondrial disease (max 500 words);
  • full project budget (including funding detail from all other sources). Separate budget requested from Lily Foundation if not for the full project (max 1 page of A4);
  • research environment & supervisory team (max 500 words); please attach CVs of all key applicants (max 2 pages to include details of current research funding and 1 page of up to 10 recent and relevant publications.);
  • confirmation of whether you would be willing for your application to be shared confidentially with Lily research funding partners.

All submissions should be submitted as a single high quality pdf document incorporating all of the above.

Please note that applications which do not follow the prescribed format, will not be accepted for review.

Application Review

Applications will be evaluated by our international expert peer review panel, based on the following criteria: 

  • contribution to treatment of mitochondrial disease & direct patient benefit
  • scientific merit/ innovation, soundness of methodology & feasibility of achieving outcomes
  • budget details (reasonable, justified and potential value of investment to The Lily Foundation)
  • track record of investigator(s) & quality of research environment to perform work efficiently/accurately

Queries or completed applications should be emailed to [email protected]

Decisions will be announced by May 2023.